Biomarker

În domeniul biomedical, un biomarker sau marker biologic este un indicator măsurabil al unei anumite stări sau condiții biologice. Biomarkerii sunt adesea măsurați și evaluați cu ajutorul probelor de sânge, urină sau țesuturi moi,^[1] cu scopul de a examina procesele biologice normale, procesele patogene sau răspunsurile farmacologice la o intervenție terapeutică.^[2] Biomarkerii sunt utilizați în numeroase domenii științifice.

Note[modificare | modificare sursă]

^ Hirsch MS, Watkins J (mai 2020). „A Comprehensive Review of Biomarker Use in the Gynecologic Tract Including Differential Diagnoses and Diagnostic Pitfalls”. Advances in Anatomic Pathology. 27 (3): 164–192. doi:10.1097/PAP.0000000000000238. PMID 31149908.
^ Biomarkers Definitions Working Group (martie 2001). „Biomarkers and surrogate endpoints: preferred definitions and conceptual framework”. Clinical Pharmacology and Therapeutics (Review). 69 (3): 89–95. doi:10.1067/mcp.2001.113989. PMID 11240971. as cited in Siderowf A, Aarsland D, Mollenhauer B, Goldman JG, Ravina B (aprilie 2018). „Biomarkers for cognitive impairment in Lewy body disorders: Status and relevance for clinical trials”. Movement Disorders (Review). 33 (4): 528–536. doi:10.1002/mds.27355. PMID 29624752.

Vezi și[modificare | modificare sursă]

[1] Hirsch MS, Watkins J (mai 2020). „A Comprehensive Review of Biomarker Use in the Gynecologic Tract Including Differential Diagnoses and Diagnostic Pitfalls”. Advances in Anatomic Pathology. 27 (3): 164–192. doi:10.1097/PAP.0000000000000238. PMID 31149908.

[BMWG_2001-2] Biomarkers Definitions Working Group (martie 2001). „Biomarkers and surrogate endpoints: preferred definitions and conceptual framework”. Clinical Pharmacology and Therapeutics (Review). 69 (3): 89–95. doi:10.1067/mcp.2001.113989. PMID 11240971. as cited in Siderowf A, Aarsland D, Mollenhauer B, Goldman JG, Ravina B (aprilie 2018). „Biomarkers for cognitive impairment in Lewy body disorders: Status and relevance for clinical trials”. Movement Disorders (Review). 33 (4): 528–536. doi:10.1002/mds.27355. PMID 29624752.

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